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| | 3,6-Dihydroxy-4,5-dimethylpyridazine Basic information | | Uses |
| Product Name: | 3,6-Dihydroxy-4,5-dimethylpyridazine | | Synonyms: | 3,6-Dihydroxy-4,5-dimethylpyridazine;3,6-DIHYDROXY-4,5-DIMETHYLPYRIDAZINE (4,5-DIMETHYLMALEIC HYDRAZIDE);4,5-Dimethylpyridazine-3,6-diol;4,5-dimethyl-1,2-dihydropyridazine-3,6-dione;4,5-dimethyl-1,2-dihydropyridazine-3,6-quinone;1,2-Dihydro-4,5-dimethyl-3,6-pyridazinedione;Dimethylmaleic acid dimethyl cyclic hydrazide;diMethylpyridazine-3,6-diol | | CAS: | 5754-17-6 | | MF: | C6H8N2O2 | | MW: | 140.14 | | EINECS: | 1312995-182-4 | | Product Categories: | Pyridazine series | | Mol File: | 5754-17-6.mol |  |
| | 3,6-Dihydroxy-4,5-dimethylpyridazine Chemical Properties |
| Melting point | 347-351 °C | | density | 1.160±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 9.08±0.60(Predicted) | | Appearance | White to off-white Solid | | InChI | InChI=1S/C6H8N2O2/c1-3-4(2)6(10)8-7-5(3)9/h1-2H3,(H,7,9)(H,8,10) | | InChIKey | QLFHLLQTPRTMLL-UHFFFAOYSA-N | | SMILES | C1(=O)NNC(=O)C(C)=C1C | | CAS DataBase Reference | 5754-17-6 |
| Hazard Codes | T | | Hazard Note | Toxic | | HS Code | 2933998090 |
| | 3,6-Dihydroxy-4,5-dimethylpyridazine Usage And Synthesis |
| Uses | 4,5-Dimethylpyridazine-3,6-diol is a useful research chemical. | | Uses | 3,6-Dihydroxy-4,5-dimethylpyridazine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | | Synthesis | 
Hydrazine hydrochloride (58 g, 552 mmol) is dissolved in hot water (300 mL) and dimethyl maleic anhydride (58 g, 460 mmol) is added in portions and the suspension stirred at reflux for 16 h. The suspension is cooled down to room temperature and the precipitate is filtered, washed with water and dried at 40° C. under vacuum to yield 4,5-dimethyl-1,2-dihydro-pyridazine-3,6-dione (36) (64 g, 99%). | | References | [1] Patent: US2010/41663, 2010, A1. Location in patent: Page/Page column 41
[2] Journal of Organic Chemistry, 1955, vol. 20, p. 707,708
[3] Journal of the American Chemical Society, 1954, vol. 76, p. 4454,4457
[4] Patent: US2011/34451, 2011, A1. Location in patent: Page/Page column 57
[5] Patent: US2011/34452, 2011, A1. Location in patent: Page/Page column 36 |
| | 3,6-Dihydroxy-4,5-dimethylpyridazine Preparation Products And Raw materials |
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