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Oxyclozanide

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CAS:2277-92-1
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CAS:2277-92-1
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Oxyclozanide manufacturers

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  • 2026-03-31
  • CAS:2277-92-1
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  • 2026-03-31
  • CAS:2277-92-1
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Related articles

Oxyclozanide Basic information
Product Name:Oxyclozanide
Synonyms:3,3’,5,5’,6-pentachloro-2,2’-dihydroxybenzanilide;2,2’-dihydroxy-3,3’,5,5’,6-pentachlorobenzanilide;2,3,5-trichloro-n-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-benzamid;2,3,5-TRICHLORO-N-(3,5-DICHLORO-2-HYDROXYPHENYL)-6-HYDROXYBENZAMIDE;OXYCLOZANIDE BPV;BPV OXYCLOZANIDE BPV;Oxycloxanide;OXYCLOZANIDE B.P
CAS:2277-92-1
MF:C13H6Cl5NO3
MW:401.46
EINECS:218-904-0
Product Categories:
Mol File:2277-92-1.mol
Oxyclozanide Structure
Oxyclozanide Chemical Properties
Melting point 77-81C
Boiling point 215C
density 1.6274 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka5.07±0.50(Predicted)
form Solid
color White to off-white
Water Solubility 29mg/L(25 ºC)
Major Applicationforensics and toxicology
pharmaceutical (small molecule)
InChIInChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
InChIKeyJYWIYHUXVMAGLG-UHFFFAOYSA-N
SMILESC(NC1=CC(Cl)=CC(Cl)=C1O)(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl
CAS DataBase Reference2277-92-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn;N,N,Xn,Xi
Risk Statements 22-50/53-36/37/38
Safety Statements 60-61-36-26
RIDADR UN 3077
WGK Germany 3
RTECS CV8576000
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
MSDS Information
Oxyclozanide Usage And Synthesis
UsesAnthelmintic
SynthesisA preparation method of Oxyclozanide (pentachloroasalamide), which takes 2, 4-dichlorophenol which is easily available in the market as a raw material, and obtains the pentachloroasalamide by nitration, reduction and condensation with 3, 5, 6-trichlorosalicylic acid.
Oxyclozanide synthesis
in vivo

Oxyclozanide (15 mg/kg (sheep), 10 mg/kg (cattle); oral administration) shows antiparasitic effectiveness in sheep and cattle[1]. Oxyclozanide (1500-5000 mg/kg; oral administration, once) induces multiple toxic symptoms in acute toxicity test of rats[2].

Animal Model:Healthy male and female Wistar rats (100-150 g)[2]
Dosage:5000, 3690, 2730, 2025 and 1500 mg/kg
Administration:Oral administration; 5000, 3690, 2730, 2025 and 1500 mg/kg; once
Result:Induced toxic symptoms of pression, rough hair, inappetence and cyanotic lips, limbs and tail. Induced swelling spleen, bleeding spots in the liver and swelling stomachs at high-dose group.
IC 50Schistosome
Oxyclozanide Preparation Products And Raw materials
Raw materials3,5,6-Trichlorosalicylic acid-->2-AMINO-4,6-DICHLOROPHENOL
Tag:Oxyclozanide(2277-92-1) Related Product Information
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