(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid

Request For Quotation
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
Company Name: BOC Sciences  
Tel: 16314854226
Email: info@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Basic information
Product Name:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Synonyms:(RS)-APICA;1H-Indene-1-carboxylic acid, 1-amino-2,3-dihydro-5-phosphono-;rac-APICA;(RS) APICA,(RS)APICA;1-Amino-2,3-dihydro-5-phosphono-1H-indene-1-carboxylic acid (ACI);(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
CAS:170847-18-4
MF:C10H12NO5P
MW:257.18
EINECS:
Product Categories:Glutamate receptor
Mol File:Mol File
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Structure
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Chemical Properties
Boiling point 559.9±60.0 °C(Predicted)
density 1+-.0.1 g/cm3(Predicted)
storage temp. Desiccate at +4°C
solubility Soluble to 100 mM in 1.1eq. NaOH
form Powder
pka1.34±0.40(Predicted)
color White to off-white
Safety Information
MSDS Information
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Usage And Synthesis
Uses(RS)-APICA is a group II metabotropic glutamate receptor antagonist.
Biological ActivityThe rigidified analog of MPPG ((RS)-a-Methyl-4-phosphonophenylglycine ); a selective group II metabotropic glutamate receptor antagonist (IC 50 = 30 μ M) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses an unusual inverse agonist-like action.
IC 50mGluR2
(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid Preparation Products And Raw materials
Tag:(RS)-1-Amino-5-phosphonoindan-1-carboxylic acid(170847-18-4) Related Product Information
LY 341495 O-Phospho-L-serine N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide L-AP4 MTEP cinnabarinic acid