- 4-Ethylresorcinol
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- $0.00 / 1KG
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2026-01-05
- CAS:2896-60-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20 mt
- 4-Ethylresorcinol
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- $5.90/ kg
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2025-02-13
- CAS:2896-60-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10 tons
- 4-Ethylresorcinol
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- $15.00 / 1KG
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2021-08-12
- CAS:2896-60-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 4-Ethylresorcinol Basic information |
| | 4-Ethylresorcinol Chemical Properties |
| Melting point | 95-98 °C (lit.) | | Boiling point | 155 °C / 10mmHg | | density | 1.0742 (rough estimate) | | refractive index | 1.5231 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Solubility in methanol; almost transparency. Soluble in alcohol. | | pka | 10.06±0.10(Predicted) | | form | Crystalline Powder | | color | Slightly beige | | BRN | 1238231 | | Cosmetics Ingredients Functions | ANTIMICROBIAL
HAIR DYEING | | InChI | 1S/C8H10O2/c1-2-6-3-4-7(9)5-8(6)10/h3-5,9-10H,2H2,1H3 | | InChIKey | VGMJYYDKPUPTID-UHFFFAOYSA-N | | SMILES | CCc1ccc(O)cc1O | | LogP | 1.731 (est) | | CAS DataBase Reference | 2896-60-8(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Benzenediol, 4-ethyl-(2896-60-8) | | EPA Substance Registry System | 4-Ethylresorcinol (2896-60-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-36 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29072100 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-Ethylresorcinol Usage And Synthesis |
| Description | 4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol has hypopigmentation effects.4-Ethylresorcinol attenuates the mRNA and protein expression of tyrosinase-related protein (TRP)-2, and has an antioxidant effect through the inhibition of lipid peroxidation. 4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol is a derivative of resorcinol. | | Chemical Properties | slightly beige crystalline powder | | Uses | It is employed as an active pharmaceutical intermediate. | | Definition | ChEBI: 4-Ethylresorcinol is a member of resorcinols. | | Synthesis Reference(s) | Synthetic Communications, 15, p. 1315, 1985 DOI: 10.1080/00397918508077280 | | Synthesis | The synthesis of 4-Ethylresorcinol is as follows:
In a three necked round bottom flask (equipped with a condensor, additional funnel and mechanical stirrer) was added 15.2 g of a combination of Raney Nickel and Ni supported on silica. (50: 50). 100 ml of a mixture of 50: 50 ethanol: water was added and the reaction was heated at reflux conditions. 15.2 g of 2,4-dihydroxy acetophenone in 100 ml of water: ethanol and 10 ml of acetic acid was placed in the additional funnel and slowly added to the mixture (dropwise). The reaction was filtered through a milipore filter to give a pale yellow solution. Concentration of this solution in vacuo gave a solid. This solid was crystalized from 1,2-dichloroethane to give 4-ethyl resorcinol in 80% isolated yield.
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| | 4-Ethylresorcinol Preparation Products And Raw materials |
| Raw materials | 4,6-diethylresorcinol-->1,3-Benzenediol, 4-ethyl-, 1,3-diacetate-->1-[2-(Acetyloxy)-4-hydroxyphenyl]ethanone-->Ethanone, 1-[2,4-bis(acetyloxy)phenyl]--->1,3-Benzenediol, 4-ethenyl--->1-(3-ETHYL-2,6-DIHYDROXYPHENYL)ETHAN-1-ONE-->3-Methylcatechol-->3,4-Dimethoxyphenol-->1-(5-bromo-2,4-dihydroxyphenyl)ethanone-->3,5-DIMETHOXY-4-HYDROXYPHENYLACETIC ACID-->4-ALLYL-2,6-DIMETHOXYPHENOL-->2-Methoxy-6-methylphenol-->3-METHOXYCATECHOL-->5-TERT-BUTYLPYROGALLOL-->2,5-DI-TERT-BUTYLPHENOL-->4-ACETYL-3-HYDROXYPHENYL ACETATE-->4-Bromoresorcinol |
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