JP 1302 2HCl

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:JP1302 dihydrochloride
CAS:1259314-65-2
Purity:99.61% Package:5mg;53USD|10mg;77USD|25mg;148USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:JP1302 dihydrochloride
CAS:1259314-65-2
Purity:99.61% Package:5mg;53USD|10mg;77USD|25mg;148USD
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:JP 1302 2HCl
CAS:1259314-65-2
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
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Email: tp@aladdinsci.com
Products Intro: Product Name:JP1302 dihydrochloride
CAS:1259314-65-2
Purity:>=99% Package:$340.9/10mg;$1090.9/50mg;Bulk package Remarks:99%
Company Name: Hefei Lbao Physical & Chemical Science Co.,Ltd
Tel: +15184799099
Email: lbaochemicals@gmail.com
Products Intro: Product Name:JP 1302 2HCl
CAS:1259314-65-2
Purity:98% Package:1kg;

JP 1302 2HCl manufacturers

  • JP 1302 2HCl
  • JP 1302 2HCl pictures
  • 2026-05-18
  • CAS:1259314-65-2
  • Min. Order: 1kg
  • Purity: 98%
JP 1302 2HCl Basic information
Product Name:JP 1302 2HCl
Synonyms:JP 1302 2HCl;JP-1302 (hydrochloride);JP-1302 HCl;N-(4-(4-Methylpiperazin-1-yl)phenyl)acridin-9-amine dihydrochloride;Inhibitor,JP 1302,JP-1302,JP1302 dihydrochloride,inhibit,JP1302,Beta Receptor,Adrenergic Receptor,JP-1302 dihydrochloride;JP1302 dihydrochloride, alpha2C antagonist;JP1302 dihydrochloride, 10 mM in DMSO
CAS:1259314-65-2
MF:C24H25ClN4
MW:404.94
EINECS:
Product Categories:
Mol File:1259314-65-2.mol
JP 1302 2HCl Structure
JP 1302 2HCl Chemical Properties
storage temp. Store at -20°C
solubility Soluble to 100 mM in water and to 5 mM in DMSO
form Powder
color Brown to reddish brown
Water Solubility Soluble to 100 mM in water
Safety Information
MSDS Information
JP 1302 2HCl Usage And Synthesis
UsesJP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
in vivo

JP1302 (1-10 μmol/kg) decreases immobility time in the FST to a level similar to that seen with 10-30 μmol/kg of the antidepressant Desipramine (HY-B1272A)[1].
JP1302 (5 μmol/kg, once) is capable of complete reversal of the impairment in PPI induced in Sprague-Dawley rats by the psychotomimetic NMDA receptor antagonist, phencyclidine and similar results are found in Wistar rats[1].
JP1302 (3 mg/kg, IV, once) significantly ameliorates renal dysfunction[3].

Animal Model:Male Sprague Dawley rats (8 weeks old)[3]
Dosage:3 mg/kg
Administration:IV, pre-treatment: administered 5 min before the induction of ischemia, post-treatment: injected 45 min after the initiation of reperfusion
Result:Significantly ameliorated renal dysfunction in the rats at 24 h after reperfusion. post-ischemic administration of JP-1302 significantly ameliorated renal dysfunction, histological damage and reduced apoptotic cells and pro-inflammatory cytokine mRNA expression.
IC 50human α2C-adrenoceptor: 28±2 nM (Ki); human α2B-adrenoceptor: 1470±130 nM (Ki); human α2A-adrenoceptor: 3150±50 nM (Ki); rodent α2D-adrenoceptor: 1700±200 nM (Ki)
storageStore at -20°C
JP 1302 2HCl Preparation Products And Raw materials
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