Bromoacetamido-PEG4-t-Butyl Ester manufacturers
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| | Bromoacetamido-PEG4-t-Butyl Ester Basic information |
| Product Name: | Bromoacetamido-PEG4-t-Butyl Ester | | Synonyms: | Bromoacetamido-PEG4-t-Butyl Ester;Bromoacetamido-PEG5-t-Butyl Ester;BrCH2CONH-PEG4-COOtBu;CAS_1807521-00-1;Bromoacetamido-PEG4-C2-Boc;4,7,10,13-Tetraoxa-16-azaoctadecanoic acid, 18-bromo-17-oxo-, 1,1-dimethylethyl ester | | CAS: | 1807521-00-1 | | MF: | C17H32BrNO7 | | MW: | 442.34 | | EINECS: | | | Product Categories: | | | Mol File: | 1807521-00-1.mol |  |
| | Bromoacetamido-PEG4-t-Butyl Ester Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Bromoacetamido-PEG4-t-Butyl Ester Usage And Synthesis |
| Description | Bromoacetamido-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | | Uses | Bromoacetamido-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether; PEGs | | References | [1] Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1. |
| | Bromoacetamido-PEG4-t-Butyl Ester Preparation Products And Raw materials |
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