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| | 2'-C-ethynyluridine Basic information |
| Product Name: | 2'-C-ethynyluridine | | Synonyms: | 2'-C-ethynyluridine;1-((2R,3R,4R,5R)-3-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;EOS-61194;2'-beta-C-Ethynyluridine;Uridine, 2'-C-ethynyl-;2’-beta-C-Ethynyluridine | | CAS: | 188413-98-1 | | MF: | C11H12N2O6 | | MW: | 268.22 | | EINECS: | | | Product Categories: | | | Mol File: | 188413-98-1.mol |  |
| | 2'-C-ethynyluridine Chemical Properties |
| | 2'-C-ethynyluridine Usage And Synthesis |
| Uses | 2'-C-Ethynyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2'-C-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 2'-C-ethynyluridine Preparation Products And Raw materials |
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