- AcS-PEG3-acid
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- $0.00 / 500mg
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2025-06-07
- CAS:1421933-33-6
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | S-acetyl-PEG3-acid Basic information |
| Product Name: | S-acetyl-PEG3-acid | | Synonyms: | 14-Oxo-4,7,10-trioxa-13-thiapentadecanoic acid;S-acetyl-PEG3-acid;Acid-PEG3-S-methyl ethanethioate;S-acetyl-PEG3-COOH;CAS_1421933-33-6;S-Acetyl-PEG3-C2-acid;4,7,10-Trioxa-13-thiapentadecanoic acid, 14-oxo-;S-acetyl-PEG-COOH | | CAS: | 1421933-33-6 | | MF: | C11H20O6S | | MW: | 280.34 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1421933-33-6.mol |  |
| | S-acetyl-PEG3-acid Chemical Properties |
| Boiling point | 421.4±40.0 °C(Predicted) | | density | 1.193±0.06 g/cm3(Predicted) | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 4.28±0.10(Predicted) |
| | S-acetyl-PEG3-acid Usage And Synthesis |
| Description | S-acetyl-PEG3-acid is a PEG linker containing a sulfur acetyl group and a terminal carboxylic acid. The sulfur acetyl group can be deprotected to produce a thiol moiety. The terminal carboxylic acid can react with primary amines in the presence of EDC or HATU to produce amide bonds. The hydrophilic PEG linker increase the water solubility of the compound in aqueous media. | | Uses | S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | S-acetyl-PEG3-acid Preparation Products And Raw materials |
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