G244-LM manufacturers
- G244-LM
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- $44.00
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2026-05-11
- CAS:1563007-08-8
- Purity: 98.46%
- Supply Ability: 10g
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| | G244-LM Basic information |
| Product Name: | G244-LM | | Synonyms: | G244-LM;4H-Thiopyrano[4,3-d]pyrimidin-4-one, 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-;Inhibitor,G244LM,G244-LM,inhibit,poly ADP ribose polymerase,PARP,G244 LM,G-244-LM;2-[4-(2-methanesulfonylphenyl)piperazin-1-yl]-1H,4H,5H,7H,8H-thiopyrano[4,3-d]pyrimidin-4-one | | CAS: | 1563007-08-8 | | MF: | C18H22N4O3S2 | | MW: | 406.52 | | EINECS: | | | Product Categories: | | | Mol File: | 1563007-08-8.mol |  |
| | G244-LM Chemical Properties |
| Boiling point | 662.4±65.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:2.0(Max Conc. mg/mL);4.92(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);12.3(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.615(Max Conc. mM) | | form | A crystalline solid | | pka | 2.83±0.40(Predicted) | | color | White to off-white |
| | G244-LM Usage And Synthesis |
| Description | G244-LM is an inhibitor of Wnt signaling. | | Uses | G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1]. | | References | [1] Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res. 2013 May 15;73(10):3132-44. DOI:10.1158/0008-5472.CAN-12-4562 |
| | G244-LM Preparation Products And Raw materials |
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