| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
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info@bocsci.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
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Cdk/Crk Inhibitor manufacturers
- RGB-286147
-
- $499.00
-
2026-07-27
- CAS:784211-09-2
- Purity:
- Supply Ability: 10g
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| | Cdk/Crk Inhibitor Basic information |
| Product Name: | Cdk/Crk Inhibitor | | Synonyms: | Cdk/Crk Inhibitor;RGB-286147;RGB 286147,RGB286147;4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1-(2,6-dichlorophenyl)-1,5-dihydro-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-(1-methylethyl)-;Cdk/Crk Inhibitor - CAS 784211-09-2 - Calbiochem[219491] | | CAS: | 784211-09-2 | | MF: | C23H22Cl2N4O3 | | MW: | 473.35 | | EINECS: | | | Product Categories: | | | Mol File: | 784211-09-2.mol |  |
| | Cdk/Crk Inhibitor Chemical Properties |
| Boiling point | 677.0±65.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml | | form | White powder solid. | | pka | 14.23±0.10(Predicted) | | color | White to off-white |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | Cdk/Crk Inhibitor Usage And Synthesis |
| Uses | Cdk/Crk Inhibitor is a pyrazolo-pyrimidinone compound that acts as a potent, selective & ATP-competitive inhibitor of Cdks. | | Biological Activity | Cell permeable: yes', 'Primary Target
Cdk1/B, Cdk2/E, Cdk3/E, Cdk5/p35, Cdk7/H/MAT1, and Cdk9', 'Product competes with ATP.', 'Reversible: no', 'Target IC50: 48 nM, 15 nM, 9 nM, 10 nM, 71 nM, and 9 nM for Cdk1/B, Cdk2/E, Cdk3/E, Cdk5/p35, Cdk7/H/MAT1, and Cdk9, respectively | | IC 50 | CDK1/cyclinB: 48 nM (IC50); CDK2/E: 15 nM (IC50); CDK4/D1: 839 nM (IC50); cdk6/cyclin D3: 232 nM (IC50) |
| | Cdk/Crk Inhibitor Preparation Products And Raw materials |
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