9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine manufacturers
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| | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine Basic information |
| Product Name: | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine | | Synonyms: | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine;2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-9H-purine;9H-Purine, 2-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(3-thienyl)-;N-[3-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxo-1,6-dihydropyrimidin-6-yl]benzamide | | CAS: | 1612192-01-4 | | MF: | C14H12ClFN4O3S | | MW: | 370.78 | | EINECS: | | | Product Categories: | | | Mol File: | 1612192-01-4.mol |  |
| | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine Chemical Properties |
| Boiling point | 552.7±60.0 °C(Predicted) | | density | 1.88±0.1 g/cm3(Predicted) | | pka | 12.40±0.70(Predicted) |
| | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine Usage And Synthesis |
| Uses | 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine Preparation Products And Raw materials |
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