1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine

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1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Basic information
Product Name:1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine
Synonyms:1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine;1-[4-(oxan-2-yloxy)phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine;Piperidine, 1-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]-
CAS:681482-80-4
MF:C23H26F3NO4
MW:437.45
EINECS:
Product Categories:
Mol File:681482-80-4.mol
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Structure
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Chemical Properties
Boiling point 530.2±50.0 °C(Predicted)
density 1.252±0.06 g/cm3(Predicted)
solubility soluble in Chloroform, DCM
pka3.84±0.20(Predicted)
form Solid
color Off-White
Safety Information
MSDS Information
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Usage And Synthesis
Uses1-[4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenyl]-4-[4-(trifluoromethoxy)phenoxy]piperidine is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine Preparation Products And Raw materials
Raw materials4-[4-(Trifluoromethoxy)phenoxy]piperidine-->2-(4-Bromophenoxy)tetrahydro-2H-pyran
Tag:1-[4-(tetrahydropyran-2-yloxy)phenyl]-4-(4-trifluoromethoxyphenoxy)piperidine(681482-80-4) Related Product Information