5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

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Company Name: Shanghai Worldyang Chemical Co.,Ltd.
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Products Intro: Product Name:Bevenopran
CAS:676500-67-7
Purity:0.98 Package:100g, 500g, 1kg, 25kg
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CAS:676500-67-7
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Products Intro: Product Name:2,6-Bis(N-pyrazolyl)Pyridine dichloronitride (II)
CAS:676500-67-7
Purity:98% Package:25KG Remarks:1097
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Products Intro: Product Name:Bevenopran
CAS:676500-67-7
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Products Intro: Product Name:Bevenopran
CAS:676500-67-7
Purity:NLT 98% Remarks:MC566770

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide manufacturers

  • Bevenopran
  • Bevenopran pictures
  • $59.00
  • 2026-05-11
  • CAS:676500-67-7
  • Purity: 98.69%
  • Supply Ability: 10g
  • Bevenopran
  • Bevenopran pictures
  • $59.00
  • 2026-05-11
  • CAS:676500-67-7
  • Purity: 98.69%
  • Supply Ability: 10g
  • Bevenopran
  • Bevenopran pictures
  • $65.00
  • 2026-05-05
  • CAS:676500-67-7
  • Min. Order: 10kg
  • Purity: 0.99
  • Supply Ability: 20tons
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Basic information
Product Name:5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
Synonyms:5-[2-methoxy-4-[[2-(oxan-4-yl)ethylamino]methyl]phenoxy]pyrazine-2-carboxamide;2-PYRAZINECARBOXAMIDE, 5-[2-METHOXY-4-[[[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHYL]AMINO]METHYL]PHENOXY]-;Bevenopran;5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide;ADL-5945;CB-5945;Inhibitor,CB 5945,Bevenopran,CB5945,inhibit,Opioid Receptor,ADL 5945,ADL5945;Bevenopran, 10 mM in DMSO
CAS:676500-67-7
MF:C20H26N4O4
MW:386.44
EINECS:
Product Categories:
Mol File:676500-67-7.mol
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Structure
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Chemical Properties
Melting point 133 - 136 °C
Boiling point 575.0±50.0 °C(Predicted)
density 1.204±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Acetonitrile (Slightly), Chloroform (Slightly)
pka14.06±0.50(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Usage And Synthesis
UsesBevenopran, is a peripheral μ-opioid receptor antagonist.
DefinitionChEBI: Bevenopran is an aromatic ether.
in vivo

Bevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD)[1]. Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively[1].

IC 50μ Opioid Receptor/MOR
5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Preparation Products And Raw materials
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