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- DNP-PEG4-COOtBu
-
-
2025-06-07
- CAS:1817735-31-1
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | DNP-PEG4-t-butyl ester Basic information |
| Product Name: | DNP-PEG4-t-butyl ester | | Synonyms: | DNP-PEG4-t-butyl ester;DNP-PEG4-COOtBu;DNP-NH-PEG4-C2-Boc;4,7,10,13-Tetraoxapentadecanoic acid, 15-[(2,4-dinitrophenyl)amino]-, 1,1-dimethylethyl ester;N-Methyl-N-Benzyl-L-Alanine;tert-Butyl 1-((2,4-dinitrophenyl)amino)-3,6,9,12-tetraoxapentadecan-15-oate | | CAS: | 1817735-31-1 | | MF: | C21H33N3O10 | | MW: | 487.5 | | EINECS: | | | Product Categories: | | | Mol File: | 1817735-31-1.mol |  |
| | DNP-PEG4-t-butyl ester Chemical Properties |
| Boiling point | 607.5±55.0 °C(Predicted) | | density | 1.241±0.06 g/cm3(Predicted) | | pka | -5.26±0.50(Predicted) |
| | DNP-PEG4-t-butyl ester Usage And Synthesis |
| Description | DNP-PEG4-t-butyl ester is a PEG linker containing DNP and t-butyl ester moieties. DNP is involved in biological pathways and participates in ion transport across membranes. The t-butyl ester can be deprotected under acidic conditions. The hydrophilic PEG linker increases water solubility of a compound in aqueous media. | | Uses | DNP-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DNP-PEG4-t-butyl ester Preparation Products And Raw materials |
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