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| | OXF BD 02 Basic information |
| Product Name: | OXF BD 02 | | Synonyms: | OXF BD 02;3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-±-phenyl-benzenemethanol;Benzenemethanol, 3-(3,5-dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-;3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-benzenemethanol;3-(3,5-Dimethylisoxazol-4-yl)-5-(hydroxy(phenyl)methyl)phenol;3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-benzenemethanol, CAS 1429129-68-9 | | CAS: | 1429129-68-9 | | MF: | C18H17NO3 | | MW: | 295.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1429129-68-9.mol |  |
| | OXF BD 02 Chemical Properties |
| Melting point | 187-190 °C(Solvent: Acetonitrile) | | Boiling point | 515.4±50.0 °C(Predicted) | | density | 1.233±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming | | form | Powder | | pka | 9.26±0.10(Predicted) | | color | White to off-white |
| | OXF BD 02 Usage And Synthesis |
| Uses | 3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenyl-benzenemethanol is bromodomain ligand acting as a selective inhibitor of the first bromodomain of BRD4. Potential applications involved decreased lifespan of lung adenocarcinoma cell lines and reduction of cell proliferation in leukemia cells. | | IC 50 | BRD4(1): 382 nM (IC50) | | storage | Store at +4°C |
| | OXF BD 02 Preparation Products And Raw materials |
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