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Adenosine, 2-chloro-N-methyl- manufacturers
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| | Adenosine, 2-chloro-N-methyl- Basic information |
| Product Name: | Adenosine, 2-chloro-N-methyl- | | Synonyms: | Adenosine, 2-chloro-N-methyl-;(2R,3R,4S,5R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;Regadenoson Impurity 43;(2R,3R,4S,5R)-2-(2-hydrazinyl-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;2-Chloro-N6-methyladenosine | | CAS: | 13406-50-3 | | MF: | C11H14ClN5O4 | | MW: | 315.71 | | EINECS: | | | Product Categories: | | | Mol File: | 13406-50-3.mol |  |
| | Adenosine, 2-chloro-N-methyl- Chemical Properties |
| Boiling point | 623.5±65.0 °C(Predicted) | | density | 1.96±0.1 g/cm3(Predicted) | | pka | 13.06±0.70(Predicted) |
| | Adenosine, 2-chloro-N-methyl- Usage And Synthesis |
| Uses | 2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | Adenosine, 2-chloro-N-methyl- Preparation Products And Raw materials |
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