Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- manufacturers
- NSC 288387
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2026-05-11
- CAS:61369-43-5
- Purity:
- Supply Ability: 10g
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| | Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Basic information |
| | Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Chemical Properties |
| Melting point | 224 °C(Solv: methanol (67-56-1)) | | Boiling point | 508.8±52.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | -1.36±0.20(Predicted) |
| | Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Usage And Synthesis |
| Uses | NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC50 of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture[1]. | | References | [1] Samrat SK, et al. Broad-Spectrum Small-Molecule Inhibitors Targeting the SAM-Binding Site of Flavivirus NS5 Methyltransferase. ACS Infect Dis. 2023 Jul 14;9(7):1319-1333. DOI:10.1021/acsinfecdis.2c00571 |
| | Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Preparation Products And Raw materials |
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