|
|
| | N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE Basic information |
| Product Name: | N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE | | Synonyms: | N-METHYL-4-NITROBENZYLAMINE HYDROCHLORIDE;N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE;N-Methyl-N-(4-nitrobenzyl)amineHCl;4-Nitro-N-methylbenzylamine;N-METHYL-N-(4-NITROBENZYL)AMINE;N-METHYL-N-(4-NITROB;N-Methyl-4-nitrobenzylaMine;Methyl[(4-nitrophenyl)Methyl]aMine hydrochloride | | CAS: | 19499-60-6 | | MF: | C8H10N2O2 | | MW: | 166.18 | | EINECS: | | | Product Categories: | Polyamines | | Mol File: | 19499-60-6.mol |  |
| | N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE Chemical Properties |
| Melting point | 218 °C | | Boiling point | 277.2±15.0 °C(Predicted) | | density | 1.162±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 8.86±0.10(Predicted) | | form | Solid | | Appearance | Brown to reddish brown Solid | | CAS DataBase Reference | 19499-60-6 |
| Hazard Codes | Xi | | HS Code | 2921490090 |
| | N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE Usage And Synthesis |
| Synthesis | GENERAL STEPS: To prepare N-methyl-4-nitrobenzylamine; 4-nitrobenzaldehyde (15.0 g, 99.3 mmol) and 40% aqueous methylamine (17 mL) in methanol (250 mL) were mixed for 15 min at 0 °C, followed by addition of sodium borohydride (3.77 g). The reaction mixture was stirred at room temperature for 2 hours and then concentrated. Water (50 mL) was added to the residue and extracted with dichloromethane (3 x 250 mL). The organic phases were combined, dried and concentrated to give the target product N-methyl-4-nitrobenzylamine. Yield 15.4 g, 94% yield.1H NMR (CDCl3) δ 8.10 (m, 2H), 7.43 (m, 2H), 3.79 (s, 2H), 2.39 (s, 3H).MS (AP+) m/e 167 (MH+). | | References | [1] Patent: WO2008/4117, 2008, A1. Location in patent: Page/Page column 116
[2] Molecules, 2017, vol. 22, # 12, |
| | N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE Preparation Products And Raw materials |
|