4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide

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Products Intro: Product Name:DDR2-IN-1
CAS:1573053-23-2
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Products Intro: Product Name:4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide
CAS:1573053-23-2
Purity:98% Package:5g;10g Remarks:AC010521
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Products Intro: Product Name:4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide
CAS:1573053-23-2
Purity:98%+ Package:10g;100g;1kg;10kg;100kg
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Products Intro: Product Name:DDR2-IN-1
CAS:1573053-23-2
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4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide Basic information
Product Name:4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide
Synonyms:4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide;DDR2 inhibitor;2-Pyridinecarboxamide, 4-[4-[[[[[4-chloro-2-[2-(dimethylamino)ethoxy]-5-methylphenyl]amino]carbonyl]amino]methyl]-2-methylphenoxy]-N-methyl-;DDR2-IN-1
CAS:1573053-23-2
MF:C27H32ClN5O4
MW:526.03
EINECS:
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Mol File:1573053-23-2.mol
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide Structure
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide Chemical Properties
Boiling point 680.7±55.0 °C(Predicted)
density 1.248±0.06 g/cm3(Predicted)
form Solid
pka13.07±0.46(Predicted)
color White to off-white
Safety Information
MSDS Information
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide Usage And Synthesis
UsesDDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1].
References[1] Margarita Wucherer-Plietker, et al. Inhibiteurs de ddr2 pour le traitement de l'arthrose. Patent WO2014032755A2.
4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide Preparation Products And Raw materials
Tag:4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide(1573053-23-2) Related Product Information
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