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8-Methoxyadenosine manufacturers
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| | 8-Methoxyadenosine Basic information |
| Product Name: | 8-Methoxyadenosine | | Synonyms: | 8-Methoxyadenosine;8-METHOXY-9-PENTOFURANOSYL-9H-PURIN-6-AMINE;Adenosine, 8-methoxy- | | CAS: | 3969-27-5 | | MF: | C11H15N5O5 | | MW: | 297.27 | | EINECS: | | | Product Categories: | | | Mol File: | 3969-27-5.mol |  |
| | 8-Methoxyadenosine Chemical Properties |
| Melting point | 205-207 °C | | Boiling point | 661.7±65.0 °C(Predicted) | | density | 1.98±0.1 g/cm3(Predicted) | | pka | 12.96±0.70(Predicted) |
| | 8-Methoxyadenosine Usage And Synthesis |
| Uses | 8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. | | References | [1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Cheeseman MD, Westwood IM, Barbeau O, et al. Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70. J Med Chem. 2016;59(10):4625-4636. DOI:10.1021/acs.jmedchem.5b02001 |
| | 8-Methoxyadenosine Preparation Products And Raw materials |
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