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Product Name:ACT 178882
CAS:1007392-69-9
Purity:4340RMB/1mg Package:>98%
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BOC Sciences
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| Products Intro: |
Product Name:ACT 178882
CAS:1007392-69-9
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Product Name:ACT 178882
CAS:1007392-69-9
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg
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| | ACT 178882 Basic information |
| Product Name: | ACT 178882 | | Synonyms: | ACT 178882;MK-1597;3-Piperidinecarboxamide, N-[[2-chloro-5-(2-methoxyethyl)phenyl]methyl]-N-cyclopropyl-4-[6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-3-pyridinyl]-, (3R,4S)- | | CAS: | 1007392-69-9 | | MF: | C33H38Cl3N3O4 | | MW: | 647.03 | | EINECS: | | | Product Categories: | | | Mol File: | 1007392-69-9.mol |  |
| | ACT 178882 Chemical Properties |
| Boiling point | 764.3±60.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | pka | 8.65±0.10(Predicted) |
| | ACT 178882 Usage And Synthesis |
| Uses | ACT 178882 is a new Renin inhibitor with an IC50 of 1.4 nM. | | References | [1] Corminboeuf O, et al. Piperidine-based renin inhibitors: upper chain optimization. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6291-6. DOI:10.1016/j.bmcl.2010.08.087
[2] Dingemanse J, et al. Drug-drug interaction study of ACT-178882, a new renin inhibitor, and diltiazem in healthy subjects. Clin Drug Investig. 2013 Mar;33(3):207-13. DOI:10.1007/s40261-013-0056-2 |
| | ACT 178882 Preparation Products And Raw materials |
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