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Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- manufacturers
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| | Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- Basic information |
| | Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- Chemical Properties |
| Boiling point | 655.0±55.0 °C(Predicted) | | density | 1.226±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 7.83±0.10(Predicted) |
| | Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- Usage And Synthesis |
| Uses | 5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. 5-HT2A antagonist 1 may be useful in treatment of gastrointestinal disorders circulatory disorders. | | Biological Activity | 5-HT2A antagonist 1 is a 5-HT2A antagonist from patents US5728835A and JP 1007727. It has potential for cardiovascular research. | | in vitro | Please refer to patent US5728835A and JP 1007727 for more information. | | target | | | IC 50 | 5-HT2A Receptor | | References | [1] Aoki Tsuyoshi, et al. Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same. US5728835A
[2] Preparation of 3-pyridylamines as 5-HT2 receptor antagonists for treatment of circulatory disorders |
| | Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- Preparation Products And Raw materials |
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