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| | NFAT inhibitor, Cell Permeable Basic information |
| Product Name: | NFAT inhibitor, Cell Permeable | | Synonyms: | NFAT inhibitor, Cell Permeable;PubChem ID: 121513885;11R-VIVIT (NFAT inhibitor);11R-VIVIT;L-Glutamic acid, L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginylglycylglycylglycyl-L-methionyl-L-alanylglycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonylglycyl-L-prolyl-L-histidyl-L-α-glutamyl-;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[( 2S)-2-[[2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino;11R-VIVIT、NFAT inhibitor, Cell Permeable | | CAS: | 592517-80-1 | | MF: | C147H259N67O36S | | MW: | 3573.12166 | | EINECS: | | | Product Categories: | | | Mol File: | 592517-80-1.mol |  |
| | NFAT inhibitor, Cell Permeable Chemical Properties |
| density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | lyophilized solid | | color | white | | Water Solubility | Soluble to 1 mg/ml in water |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | NFAT inhibitor, Cell Permeable Usage And Synthesis |
| Uses | Use at 1 μM for preventing the activation and proliferation of T cells | | Biological Activity | Primary Target
NFAT | | in vivo | 11R-VIVIT significantly abrogates the increased urinary albumin excretion rates, attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement, partially restores podocyte number, inhibits NFAT2 activation and uPAR expression in glomerular podocytes[1]. | | storage | Store at -20°C |
| | NFAT inhibitor, Cell Permeable Preparation Products And Raw materials |
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