| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-400-164-7117 18317119277 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:14,14,14-Trifluoro-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate
CAS:1872433-61-8
Purity:95% Package:100mg;250mg;1g Remarks:BD00862821
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1,1,1-Trifluoroethyl-PEG5-Tos manufacturers
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| | 1,1,1-Trifluoroethyl-PEG5-Tos Basic information |
| Product Name: | 1,1,1-Trifluoroethyl-PEG5-Tos | | Synonyms: | 1,1,1-Trifluoroethyl-PEG5-Tos;1,1,1-Trifluoroethyl-PEG4-Tos;3,6,9,12-Tetraoxatetradecan-1-ol, 14,14,14-trifluoro-, 1-(4-methylbenzenesulfonate);1,1,1-Trifluoroethyl-PEG5-p-phenylsulfonate ester;14,14,14-Trifluoro-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate | | CAS: | 1872433-61-8 | | MF: | C17H25F3O7S | | MW: | 430.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1872433-61-8.mol |  |
| | 1,1,1-Trifluoroethyl-PEG5-Tos Chemical Properties |
| Boiling point | 495.8±45.0 °C(Predicted) | | density | 1.250±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Viscous Liquid | | color | Colorless to light yellow |
| | 1,1,1-Trifluoroethyl-PEG5-Tos Usage And Synthesis |
| Description | 1,1,1-Trifluoroethyl-PEG5-Tos has a trifluoroethyl and tosyl attached to it. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | | Uses | 1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 1,1,1-Trifluoroethyl-PEG5-Tos Preparation Products And Raw materials |
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