Hydroxy-PEG3-methylamine manufacturers
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| | Hydroxy-PEG3-methylamine Basic information |
| Product Name: | Hydroxy-PEG3-methylamine | | Synonyms: | Hydroxy-PEG3-methylamine;MeNH-PEG4-OH;Hydroxy-PEG4-methylamine;Methylamino-PEG4-alcohol;MeNH-PEG4-OH/5,8,11-Trioxa-2-azatridecan-13-ol;2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethanol;5,8,11-Trioxa-2-azatridecan-13-ol | | CAS: | 90430-59-4 | | MF: | C9H21NO4 | | MW: | 207.27 | | EINECS: | | | Product Categories: | | | Mol File: | 90430-59-4.mol |  |
| | Hydroxy-PEG3-methylamine Chemical Properties |
| storage temp. | 2-8°C, protect from light | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Light yellow to orange |
| | Hydroxy-PEG3-methylamine Usage And Synthesis |
| Description | Hydroxy-PEG3-methylamine is a PEG linker containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. | | Uses | Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Hydroxy-PEG3-methylamine Preparation Products And Raw materials |
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