m-PEG5-Ms

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m-PEG5-Ms Basic information
Product Name:m-PEG5-Ms
Synonyms:m-PEG5-Ms;2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate;2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate;PEG4-Oms;m-PEG4-OMs
CAS:130955-37-2
MF:C10H22O7S
MW:286.34
EINECS:
Product Categories:
Mol File:130955-37-2.mol
m-PEG5-Ms Structure
m-PEG5-Ms Chemical Properties
storage temp. Storage temp. 2-8°C
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
m-PEG5-Ms Usage And Synthesis
Descriptionm-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Usesm-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Biological Activitym-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
target

Cleavable

PEGs

IC 50Cleavable Linker; PEGs
References[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
m-PEG5-Ms Preparation Products And Raw materials
Tag:m-PEG5-Ms(130955-37-2) Related Product Information
mPEG12-Br 2,5,8,11,14,17,20,23-Octaoxapentacosane-25-thiol mPEG7-Alkyne mPEG11-Br Bromo-PEG24-methoxy MPEG8-N3 2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol mPEG3-CH2COOH Proparyl-PEG5-methane MPEG3-Propyne 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol mPEG16-Br 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol 2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol H2N-PEG11-CH2CH2COOH FMoc-NH-PEG7-CH2CH2COOH

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