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T&W GROUP |
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021-61551611 13296011611 |
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contact@trustwe.com |
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| | m-PEG5-Ms Basic information |
| Product Name: | m-PEG5-Ms | | Synonyms: | m-PEG5-Ms;2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate;2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate;PEG4-Oms;m-PEG4-OMs | | CAS: | 130955-37-2 | | MF: | C10H22O7S | | MW: | 286.34 | | EINECS: | | | Product Categories: | | | Mol File: | 130955-37-2.mol |  |
| | m-PEG5-Ms Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | m-PEG5-Ms Usage And Synthesis |
| Description | m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | Biological Activity | m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs). | | target | | Cleavable | PEGs | table>| IC 50 | Cleavable Linker; PEGs | | References | [1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1. |
| | m-PEG5-Ms Preparation Products And Raw materials |
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Tag:m-PEG5-Ms(130955-37-2)
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