N-(Azido-PEG3)-N-Boc-PEG4-NHS ester

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:N-(Azido-PEG4)-N-Boc-PEG4-NHS ester
CAS:2112731-96-9
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
CAS:2112731-96-9
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
CAS:2112731-96-9
Purity:>95.00% Package:500mg
Company Name: Aladdin Scientific
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
CAS:2112731-96-9
Purity:98% Package:$1051.9/100mg;$2041.9/250mg;$3301.9/500mg;Bulk package Remarks:98%
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
CAS:2112731-96-9
Purity:98% Package:1g;5g;25g;100g

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester manufacturers

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Basic information
Product Name:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
Synonyms:N-(Azido-PEG3)-N-Boc-PEG4-NHS ester;N-(Azido-PEG4)-N-Boc-PEG4-NHS ester;HUN 31969
CAS:2112731-96-9
MF:C28H49N5O13
MW:663.71436
EINECS:
Product Categories:
Mol File:2112731-96-9.mol
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Structure
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Chemical Properties
storage temp. -20°C, sealed storage, away from moisture
form Liquid
color Colorless to off-white
Safety Information
MSDS Information
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Usage And Synthesis
DescriptionN-(Azido-PEG3)-N-Boc-PEG4-NHS ester is a branched PEGylation reagent with a terminal azide group (N3), a Boc protected amine (NH2), and a terminal NHS ester.The azide group enables PEGylation via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The protected amine can be deprotected under acidic conditions.
UsesN-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs[1] N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50PEGs
References[1] Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. DOI:10.1016/j.jconrel.2016.02.017
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Preparation Products And Raw materials
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