| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
|
| | ANTI-PTB Basic information |
| Product Name: | ANTI-PTB | | Synonyms: | POLYPYRIMIDINE TRACT BINDING PROTEIN (AB-1) MONOCLONAL ANTIBODY;Anti-PTBP2, (N-terminal) antibody produced in rabbit;Anti-PTBP2 antibody produced in rabbit;Monoclonal Anti-PTBP1 antibody produced in mouse;Anti-PTBP1/PTB antibody produced in goat;ANTI-POLYPIRIMIDINE TRACK BINDING PROTEIN (3);ANTI-POLYPIRIMIDINE TRACT BINDING PROTEIN (1);ANTI-POLYPYRIMIDINE TRACT BINDING PROTEIN (7) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-PTB Structure]() |
| | ANTI-PTB Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| Storage Class | 10 - Combustible liquids |
| | ANTI-PTB Usage And Synthesis |
| Uses | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. (provided by RefSeq) | | Biological Activity | The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrim |
| | ANTI-PTB Preparation Products And Raw materials |
|