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| | 4-Nitro N-butyl aniline Basic information |
| Product Name: | 4-Nitro N-butyl aniline | | Synonyms: | N-Butyl-4-nitroaniline;1-[Butylamino]-4-nitrobenzene;N-Butyl-4-nitrobenzenamine;Benzenamine, N-butyl-4-nitro-;4-Nitro N-butyl aniline | | CAS: | 58259-34-0 | | MF: | C10H14N2O2 | | MW: | 194.23 | | EINECS: | | | Product Categories: | | | Mol File: | 58259-34-0.mol |  |
| | 4-Nitro N-butyl aniline Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| | 4-Nitro N-butyl aniline Usage And Synthesis |
| Synthesis | Using 4-nitrophenol (209 mg, 1.5 mmol) and n-butylamine (2.9 mL, 30 mmol), 4-nitrophenol was dissolved in N,N-dimethylformamide (2 mL) under nitrogen protection, n-butylamine was added, and the reaction was carried out for 9 hours at 120 °C. After completion of the reaction, it was cooled to room temperature and the reaction mixture was poured into water (16 mL) and extracted with dichloromethane (3 x 5 mL). The organic phases were combined, washed with saturated saline (2 × 4 mL), dried over anhydrous sodium sulfate, filtered and concentrated. Purification by silica gel column chromatography with the eluent of dichloromethane:methanol (100:1, v/v) gave the target product N-butyl-4-nitroaniline as a yellow liquid in 64% yield. | | References | [1] Patent: CN106631820, 2017, A. Location in patent: Paragraph 0035; 0036; 0037; 0038 |
| | 4-Nitro N-butyl aniline Preparation Products And Raw materials |
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