1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one

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1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one manufacturers

  • BRD4-IN-4
  • BRD4-IN-4 pictures
  • $50.00
  • 2026-07-15
  • CAS:304685-40-3
  • Purity: 99.97%
  • Supply Ability: 10g
1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one Basic information
Product Name:1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one
Synonyms:1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one;Benz[cd]indol-2(1H)-one, 1-ethyl-6-(1-pyrrolidinylsulfonyl)-;WAY-383515;BRD4-IN-4
CAS:304685-40-3
MF:C17H18N2O3S
MW:330.4
EINECS:
Product Categories:
Mol File:304685-40-3.mol
1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one Structure
1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one Chemical Properties
form Solid
color Brown to reddish brown
Safety Information
MSDS Information
1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one Usage And Synthesis
UsesBRD4-IN-4 (Compound 1) is a BRD4 inhibitor (IC50=6.83 μM). BRD4-IN-4 selectively inhibits MV4-11 cell line proliferation and arrests cell at G1 phase. BRD4-IN-4 can be used for research of MLL leukemia[1].
References[1] Feng Y, et al. Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors. Eur J Med Chem. 2018 May 25;152:264-273. DOI:10.1016/j.ejmech.2018.04.048
1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one Preparation Products And Raw materials
Tag:1-ethyl-6-(pyrrolidin-1-ylsulfonyl)benzo[cd]indol-2(1H)-one(304685-40-3) Related Product Information
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