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| | 3,4-dihydroxyphenylacetone Basic information |
| | 3,4-dihydroxyphenylacetone Chemical Properties |
| Melting point | -30 °C (decomp) | | Boiling point | 170-173 °C(Press: 0.3 Torr) | | density | 1.251±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | powder | | pka | 9.59±0.10(Predicted) | | color | White to Very Dark Brown | | Stability: | Light Sensitive | | InChI | InChI=1S/C9H10O3/c1-6(10)4-7-2-3-8(11)9(12)5-7/h2-3,5,11-12H,4H2,1H3 | | InChIKey | JQXBETDGCMQLMK-UHFFFAOYSA-N | | SMILES | C(C1=CC=C(O)C(O)=C1)C(=O)C | | CAS DataBase Reference | 2503-44-8 |
| | 3,4-dihydroxyphenylacetone Usage And Synthesis |
| Description | 3'',4''-Dihydroxyphenylacetone (Item No. 19522) is an analytical reference standard. It is a minor metabolite of 3,4-MDEA (Item Nos. 14085 | 15689), MDMA, and α-methyldopa produced by oxidative deamination. This product is intended for forensic and research applications. | | Description | 3',4'-Dihydroxypropiophenone, also known as DOPA, is a metabolite of dopamine, which is produced in the brain and kidneys. DOPA is a precursor to the synthesis of melanin, which is found in skin cells. Glutamate dehydrogenase converts DOPA to 3-methoxytyramine, which can be detected chromatographically in urine samples. Examining a urine sample for DOPA testing can be used to diagnose Parkinson's disease. DOPA may also be detected in plasma in patients with bacterial and urinary tract infections | | Chemical Properties | Thick Yellow Oil | | Uses | 3',4'-Dihydroxyphenylacetone , MDMA, and α-methyldopa produced by oxidative deamination. This product is intended for forensic and research applications. | | Uses | A metabolite of racemic 3,4-methylenedioxyethylamphetamine. | | Production Methods | 3,4-dihydroxylphenylacetaldehyde (DHPAA) synthase catalyzes a complicated decarboxylation-deamination process of α-methyl dopa (AMD), leading to the production of 3,4-dihydroxyphenylacetone.
 | | Definition | ChEBI: 3,4-Dihydroxyphenylacetone is an alkylbenzene. | | References | [1] H. K. LIM R. L F. In vivo and in vitro metabolism of 3,4-(methylenedioxy)methamphetamine in the rat: identification of metabolites using an ion trap detector[J]. Chemical Research in Toxicology, 1988, 1 6: 370-378. DOI: 10.1021/tx00006a008
[2] H K ENSSLIN. Metabolism of racemic 3,4-methylenedioxyethylamphetamine in humans. Isolation, identification, quantification, and synthesis of urinary metabolites.[J]. Drug Metabolism and Disposition, 1996, 24 8: 813-820.
[3] MARIARITA BERTOLDI. Reaction of Dopa Decarboxylase with α-Methyldopa Leads to an Oxidative Deamination Producing 3,4-Dihydroxyphenylacetone, an Active Site Directed Affinity Label[J]. Biochemistry Biochemistry, 1998, 37 18: 6552-6561. DOI: 10.1021/bi9718898 |
| | 3,4-dihydroxyphenylacetone Preparation Products And Raw materials |
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