2-ethyl-1-hydroxy-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile manufacturers
- GNF7686
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- $1980.00
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2026-05-11
- CAS:442567-43-3
- Purity:
- Supply Ability: 10g
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| | 2-ethyl-1-hydroxy-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile Basic information |
| | 2-ethyl-1-hydroxy-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile Chemical Properties |
| density | 1.27±0.1 g/cm3(Predicted) | | pka | 3.45±0.53(Predicted) |
| | 2-ethyl-1-hydroxy-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile Usage And Synthesis |
| Description | GNF7686 is a novel inhibitor of Trypanosoma cruzi, the causative agent of Chagas disease. | | Uses | GNF7686 is a cytochrome b inhibitor. GNF7686 exhibits inhibitory activity against complex III in the extracts of L. donovani and T. cruzi[1]. | | References | [1] Wall RJ, et al. The Q Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani. ACS Infect Dis. 2020 Mar 13;6(3):515-528. DOI:10.1021/acsinfecdis.9b00426 |
| | 2-ethyl-1-hydroxy-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile Preparation Products And Raw materials |
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