- 4-Fluoro-3-nitroaniline
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- $0.00 / 1KG
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2026-01-20
- CAS:364-76-1
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- 4-Fluoro-3-nitroaniline
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- $25.00 / 1KG
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2026-01-05
- CAS:364-76-1
- Min. Order: 100KG
- Purity: 99.5%
- Supply Ability: 100 mt
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| | 4-Fluoro-3-nitroaniline Basic information |
| | 4-Fluoro-3-nitroaniline Chemical Properties |
| Melting point | 94-96 °C (lit.) | | Boiling point | 331.3±22.0 °C(Predicted) | | density | 0.43 g/cm3 (20℃) | | Fp | 196 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 2.36±0.10(Predicted) | | form | Powder | | color | Ochre | | Water Solubility | Insoluble | | BRN | 2210199 | | InChI | InChI=1S/C6H5FN2O2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H,8H2 | | InChIKey | LLIOADBCFIXIEU-UHFFFAOYSA-N | | SMILES | C1(N)=CC=C(F)C([N+]([O-])=O)=C1 | | CAS DataBase Reference | 364-76-1(CAS DataBase Reference) | | NIST Chemistry Reference | Benzenamine, 4-fluoro-3-nitro-(364-76-1) | | EPA Substance Registry System | 4-Fluoro-3-nitroaniline (364-76-1) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38-22 | | Safety Statements | 36/37-37/39-26 | | RIDADR | UN 1325 4.1/PG 2 | | WGK Germany | 2 | | RTECS | BY1700000 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29214210 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 2 |
| | 4-Fluoro-3-nitroaniline Usage And Synthesis |
| Chemical Properties | whitetolightyellowcrystalpowde | | Uses | 4-Fluoro-3-nitroaniline is used in the preparation of commercial hair dyes. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals. | | Uses | 4-Fluoro-3-nitroaniline was used in the preparation of commercial hair dyes. | | Definition | ChEBI: 4-fluoro-3-nitroaniline is a nitroaniline and an organofluorine compound. | | Synthesis | Example 43: General procedure for the synthesis of 4-fluoro-3-nitroaniline and 2-fluoro-5-nitroaniline from 2,4-dinitrofluorobenzene. A hydrogenation reaction was carried out according to the method described in Example 25 using 5% rhodium/alumina as a catalyst. This was done as follows: 18.61 g (0.10 mol) of 2,4-dinitrofluorobenzene was dissolved in a solvent mixture of 100 ml of glacial acetic acid and 100 ml of anhydrous ethanol in the presence of an alumina hydrogenation catalyst containing 0.50 g of rhodium. The hydrogen pressure was maintained at 370 psi during the reaction and the reaction time was 2 hours. Upon completion of the reaction, the product was separated by column chromatography to afford 2.79 g of 2-fluoro-5-nitroaniline in 17.6% yield. In addition, 0.85 g of 4-fluoro-3-nitroaniline was recovered as a second fraction. | | References | [1] Tetrahedron Letters, 1990, vol. 31, # 43, p. 6141 - 6144
[2] Tetrahedron Letters, 1990, vol. 31, # 43, p. 6141 - 6144
[3] Patent: US5105012, 1992, A
[4] Recueil des Travaux Chimiques des Pays-Bas, 1946, vol. 65, p. 329,330
[5] Russian Journal of General Chemistry, 2006, vol. 76, # 1, p. 76 - 81 |
| | 4-Fluoro-3-nitroaniline Preparation Products And Raw materials |
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