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| | 5-Bromo-2-hydrazinopyridine Basic information |
| | 5-Bromo-2-hydrazinopyridine Chemical Properties |
| Melting point | 132.0 to 136.0 °C | | Boiling point | 238.2±50.0 °C(Predicted) | | density | 1.82±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | form | powder to crystal | | pka | 8.97±0.70(Predicted) | | color | White to Light yellow to Light orange | | InChI | 1S/C5H6BrN3/c6-4-1-2-5(9-7)8-3-4/h1-3H,7H2,(H,8,9) | | InChIKey | QYQLEYTXFMOLEI-UHFFFAOYSA-N | | SMILES | NNc1ccc(Br)cn1 | | CAS DataBase Reference | 77992-44-0(CAS DataBase Reference) |
| Hazard Codes | Xi,T | | Risk Statements | 25-37/38-41 | | Safety Statements | 26-36-45 | | RIDADR | 2811 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | Ⅲ | | HS Code | 2933399990 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 5-Bromo-2-hydrazinopyridine Usage And Synthesis |
| Synthesis | 2-Chloro-5-bromopyridine (64 g, 333 mmol) was suspended in hydrazine monohydrate (250 mL), and the mixture was heated at 70° C. for 72 hours. The reaction mixture was then diluted with water (750 mL), and the resulting precipitate was filtered off and azeotrope, firstly with toluene (*2) and then dichloromethane (*2), to afford 5-Bromo-2-hydrazinopyridine as a pale brown solid in 83percent yield, 52 g. | | References | [1] Patent: US2006/35922, 2006, A1. Location in patent: Page/Page column 31
[2] Patent: WO2007/91152, 2007, A1. Location in patent: Page/Page column 48
[3] Patent: WO2012/65546, 2012, A1. Location in patent: Page/Page column 19
[4] Patent: WO2012/65297, 2012, A1. Location in patent: Page/Page column 19
[5] Patent: US2010/305085, 2010, A1. Location in patent: Page/Page column 17 |
| | 5-Bromo-2-hydrazinopyridine Preparation Products And Raw materials |
| Raw materials | 5-Bromo-2-fluoropyridine-->2,5-Dibromopyridine-->5-Bromo-2-chloropyridine | | Preparation Products | 6-Bromo-3-(4-bromo-2-methylphenyl)-[1,2,4]triazolo[4,3-a]pyridine-->6-BROMO-3-PHENYL-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-->1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2,3-diMethyl- |
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