| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:2-[2-(5-bromofuran-2-yl)-4-oxochromen-3-yl]oxyacetamide
CAS:819827-50-4
Purity:98% Package:50MG;100MG,1G,5G,100G
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CB7993113
CAS:819827-50-4
Package:50mg;10mg
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| Company Name: |
OTAVA chemicals
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| Tel: |
416 305 9979 (Canada) |
| Email: |
north.america@otavachemicals.com |
| Products Intro: |
CAS:819827-50-4
Purity:90%+ Package:5μmol Remarks:C15H10BrNO5
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| | 2-[2-(5-bromofuran-2-yl)-4-oxochromen-3-yl]oxyacetamide Basic information |
| | 2-[2-(5-bromofuran-2-yl)-4-oxochromen-3-yl]oxyacetamide Chemical Properties |
| Boiling point | 572.9±50.0 °C(Predicted) | | density | 1.72±0.1 g/cm3(Predicted) | | form | Solid | | pka | 15.30±0.40(Predicted) | | color | White to yellow |
| | 2-[2-(5-bromofuran-2-yl)-4-oxochromen-3-yl]oxyacetamide Usage And Synthesis |
| Uses | CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively[1]. | | in vivo | CB7993113 effectively blocks acute, 50 mg/kg DMBA-induced hepatic CYP1A1 induction and bone marrow toxicity in vivo[1].
| | References | [1] Parks AJ, et al. In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo. Mol Pharmacol. 2014 Nov;86(5):593-608. DOI:10.1124/mol.114.093369 |
| | 2-[2-(5-bromofuran-2-yl)-4-oxochromen-3-yl]oxyacetamide Preparation Products And Raw materials |
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