N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide

N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Suppliers list
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N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Basic information
Product Name:N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
Synonyms:(1aS,7E,7aS)-7,7a-Dihydro-7-(hydroxyimino)-N-phenylbenzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide;(1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide;Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, 7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (1aS,7E,7aS)-;PHCCC;N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
CAS:1161205-27-1
MF:C17H14N2O3
MW:294.31
EINECS:
Product Categories:Glutamate
Mol File:Mol File
N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Structure
N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Chemical Properties
Boiling point 579.1±50.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at RT
pka10.79±0.40(Predicted)
Safety Information
MSDS Information
N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Usage And Synthesis
Biological ActivityGroup I metabotropic glutamate receptor antagonist (IC 50 ~ 3 μ M); 67 times more potent than (S)-4-carboxyphenylglycine ((S)-4-Carboxyphenylglycine). Also a positive allosteric modulator for mGlu 4a ; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro . Displays antiParkinsonian effects in rats in vivo .
N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide Preparation Products And Raw materials
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