Sign in | Register | china | japan | germany

2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol

Request For Quotation
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Suppliers list
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:KRAS inhibitor-3
CAS:900897-56-5
Purity:99% Package:$300.9/5mg;$450.9/10mg;$950.9/25mg;$1520.9/50mg;$2420.9/100mg;Bulk package Remarks:99%
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:KRAS inhibitor-3
CAS:900897-56-5
Package:100mg;1990USD|25mg;970USD|50mg;1260USD
Company Name: Angel Pharmatech, Ltd.  
Tel: 17317130613
Email: 3358272972@qq.com
Products Intro: Product Name:KRAS inhibitor 11
CAS:900897-56-5
Package:1g/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:KRAS inhibitor-3
CAS:900897-56-5
Package:100mg/RMB 17500;25mg/RMB 9700;50mg/RMB 12600
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com; 18616537568
Email: hanfangpharma@126.com
Products Intro: Product Name:2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol
CAS:900897-56-5
Purity:98%+ Package:1g；5g；10g；100g; 1kg

2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol manufacturers

  • KRAS inhibitor-11
  • KRAS inhibitor-11 pictures
  • $2120.00 / 25mg
  • 2026-01-04
  • CAS:
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Basic information
Product Name:2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol
Synonyms:2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol;KRAS inhibitor 11;1-Piperazineethanol, 4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)-;KRAS inhibitor-3
CAS:900897-56-5
MF:C25H27N5O
MW:413.51
EINECS:
Product Categories:
Mol File:900897-56-5.mol
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Structure
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Chemical Properties
density 1.25±0.1 g/cm3(Predicted)
form Solid
pka14.96±0.10(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Usage And Synthesis
UsesKRAS inhibitor-3 is an inhibitor of KRAS inhibitor. KRAS inhibitor-3 binds to WT and oncogenic KRAS mutants with high affinity (KD: 0.28 μM for KRAS WT, 0.63 μM for KRAS G12C, 0.37 μM for KRAS G12D, 0.74 μM for KRAS Q61H). KRAS inhibitor-3 also disrupts interaction of KRAS with Raf[1].
IC 50K-Ras WT: 0.28 μM (EC50); KRAS(G12C): 0.63 μM (EC50); KRas G12D: 0.37 μM (EC50); KRas Q61H: 0.74 μM (EC50)
References[1] McCarthy MJ, et al. Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding. ACS Omega. 2019 Feb 28;4(2):2921-2930. DOI:10.1021/acsomega.8b03308
2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol Preparation Products And Raw materials
Tag:2-[4-(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl]ethanol(900897-56-5) Related Product Information
  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.