- Solvent Red 43
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- $0.00 / 1kg
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2026-05-08
- CAS:15086-94-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20MT
- Solvent Red 43
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- $1.00 / 25kg
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2025-06-27
- CAS:15086-94-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500000kg
- Eosin Y（Alcohol soluble）
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- $1.00 / 1KG
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2024-04-30
- CAS:15086-94-9
- Min. Order: 25KG
- Purity: 99%
- Supply Ability: 500 kgs per month
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| | Solvent Red 43 Basic information |
| Product Name: | Solvent Red 43 | | Synonyms: | BROMO ACID J;BROMO ACID J TS, XL, OR XX;BROMOFLUORESCEIN;BRONZE BROMO ES;EOSIN Y;EOSIN Y DISODIUM SALT;EOSIN YELLOWISH WATER-SOLUBLE;EOSIN YELLOWISH Y | | CAS: | 15086-94-9 | | MF: | C20H8Br4O5 | | MW: | 647.89 | | EINECS: | 239-138-3 | | Product Categories: | marker;Organics | | Mol File: | 15086-94-9.mol |  |
| | Solvent Red 43 Chemical Properties |
| Melting point | 300 °C | | Boiling point | 640.3±55.0 °C(Predicted) | | density | 1.02 g/mL at 20 °C | | refractive index | 1.5000 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | H2O: 0.1 g/mL, dark red | | pka | 6.97±0.20(Predicted) | | form | Liquid | | Colour Index | 45380:2 | | color | White to Light yellow to Red | | λmax | 524 nm | | Henry's Law Constant | 4.4×1012 mol/(m3Pa) at 25℃, Zhang et al. (2010) | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Major Application | diagnostic assay manufacturing
hematology
histology | | Cosmetics Ingredients Functions | COLORANT | | InChI | 1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H | | InChIKey | DBZJJPROPLPMSN-UHFFFAOYSA-N | | SMILES | Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br | | CAS DataBase Reference | 15086-94-9 | | IARC | 3 (Vol. 15, Sup 7) 1987 | | EPA Substance Registry System | Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy- (15086-94-9) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26-24/25 | | RIDADR | UN 1170 3/PG 2 | | WGK Germany | 3 | | RTECS | LM5850000 | | TSCA | TSCA listed | | REACH Registrations | Active | | HS Code | 32041919 | | Storage Class | 11 - Combustible Solids |
| | Solvent Red 43 Usage And Synthesis |
| Chemical Properties | orange-brown powder | | Uses | Eosin Acid C.I. No. 45380 (CAS# 15086-94-9) is a photo-senseitive organic catalyst and has been used in the photocatalytic, diastereoselective additions of 1-sulfoximidoyl-1,2-benziodoxoles to styrenes, and in the stereoselective synthesis of 2-deoxyglycosides from glycals. Dyes and metabolites. | | Definition | ChEBI: Bromoeosin is an organobromine compound. It is functionally related to a fluorescein (lactone form). | | Preparation | Fluorescein (C.I. Acid Yellow 73, C.I. 45350) in water or ethanol solution bromide into four bromine derivatives, And made into a free acid form.. | | Biological Activity | Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains. | | Synthesis | The general procedure for the synthesis of 2',4',5',7'-tetrabromo-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene]-3-one from 3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene] is as follows: fluorescein in the form of the lactone (1 eq.), NaBr (16 eq.), and Oxone ( 6 equiv, 2KHSO5-KHSO4-K2SO4) were mixed and ground in an agate mortar until uniformly fine. The resulting solid mixture was reacted in an oven at 200 °C for 12 h. Upon completion of the reaction, the target product tetrabromofluorescein (4Br-F) was obtained in near 100% yield in the commercial disodium salt form known as eosin Y. The reaction mixture was diluted with water and the product was extracted with ethyl acetate. The product was characterized by mass spectrometry (ESI-MS) and spectroscopic techniques (1H-NMR and 13C-NMR). The specific data were as follows: ESI-MS (+) of 4Br-F: m/z 670.4 [M + H]+; 1H NMR (CH3OD): δ 7.04 ppm (s, 1H and 8H), 7.23 (d, J = 8.0 Hz, 3H), 7.72 (ddd, J = 8.0, 8.0, 1.2 Hz, 5H), 7.79 (ddd, J = 8.0, 8.0, 1.2 Hz, 4H), 8.09 ppm (d, J = 8.0 Hz, 6H). | | Properties and Applications | brilliant yellow red. Soluble in water and ethanol for blue light red, with yellow green fluorescence. In concentrated sulfuric acid to yellow, dilution after yellow red precipitation. | | References | [1] Patent: US2008/61289, 2008, A1. Location in patent: Page/Page column 6-7
[2] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 216
[3] Journal of the American Chemical Society, 1927, vol. 49, p. 1278
[4] Justus Liebigs Annalen der Chemie, 1876, vol. 183, p. 31
[5] Justus Liebigs Annalen der Chemie, 1910, vol. 372, p. 109 |
| | Solvent Red 43 Preparation Products And Raw materials |
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