DESMETHYL LOPERAMIDE

DESMETHYL LOPERAMIDE Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:N-Desmethyl Loperamide CAS:66164-07-6 Package:5mg;2460USD\|1mg;825USD

Company Name:	Finetech Industry Limited
Tel:	+86-27-8746-5837 +8619945049750
Email:	info@finetechnology-ind.com
Products Intro:	Product Name:N-Desmethyl Loperamide CAS:66164-07-6 Purity:98% Package:1g,10g,25g,100g,500g,1kg Remarks:N/A

Company Name:	Zhejiang J&C Biological Technology Co.,Limited
Tel:	+1-2135480471 +1-2135480471;
Email:	sales@sarms4muscle.com
Products Intro:	Product Name:DESMETHYL LOPERAMIDE CAS:66164-07-6 Purity:99% Package:1gram;USD

Company Name:	sgtlifesciences pvt ltd
Tel:	+8617013299288
Email:	dj@sgtlifesciences.com
Products Intro:	Product Name:Desmethyl Loperamide

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354;
Email:	support@targetmol.com
Products Intro:	Product Name:N-Desmethyl Loperamide；dLop;R-20905;R 20905;R20905 CAS:66164-07-6 Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

DESMETHYL LOPERAMIDE manufacturers

DESMETHYL LOPERAMIDE Basic information

Product Name:	DESMETHYL LOPERAMIDE
Synonyms:	DESMETHYL LOPERAMIDE;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;N-Desmethyl Loperamide;R 20905;Desmethyl loperamide HCl;Desmethylloperamide D5;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
CAS:	66164-07-6
MF:	C28H31ClN2O2
MW:	463.01
EINECS:
Product Categories:	Amines;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	66164-07-6.mol

DESMETHYL LOPERAMIDE Chemical Properties

Melting point	219-221?C
Boiling point	678.3±55.0 °C(Predicted)
density	1?+-.0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml
form	A crystalline solid
pka	13.85±0.20(Predicted)

Safety Information

HS Code

9999999999

MSDS Information

DESMETHYL LOPERAMIDE Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function
Uses	Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
Definition	ChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.

DESMETHYL LOPERAMIDE Preparation Products And Raw materials

Tag:DESMETHYL LOPERAMIDE(66164-07-6) Related Product Information

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