| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Chevalone C
CAS:1318025-77-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | Chevalone C Basic information |
| Product Name: | Chevalone C | | Synonyms: | Chevalone C;1H,11H-Phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one, 2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-, (2S,4aR,4bR,6aS,12aS,12bR,14aR)-;(2S,4aR,4bR,6aS,12aS,12bR,14aR)-2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one | | CAS: | 1318025-77-2 | | MF: | C28H40O5 | | MW: | 456.61 | | EINECS: | | | Product Categories: | | | Mol File: | 1318025-77-2.mol |  |
| | Chevalone C Chemical Properties |
| Boiling point | 541.2±50.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | A solid |
| | Chevalone C Usage And Synthesis |
| Description | Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells. | | Uses | Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2]. | | Definition | ChEBI: Chevalone C is an organooxygen compound and an organic heterotricyclic compound. | | References | [1] Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6. DOI:10.1080/14786419.2015.1017724
[2] M Prata-Sena, et al. Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871. DOI:10.1002/ptr.5696 |
| | Chevalone C Preparation Products And Raw materials |
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