BMS-929075

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:BMS-929075
CAS:1217338-97-0
Purity:98% Package:1mg;190USD|5mg;480USD|10mg;687USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name: BMS-929075
CAS:1217338-97-0
Purity:95.0%-99.0% Package:1ASSAYS;6.05USD
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:BMS-929075
CAS:1217338-97-0
Purity:98% Package:1mg;5mg;10mg
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Email: market@ubiochem.com
Products Intro: Product Name:BMS-929075
CAS:1217338-97-0
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:BMS-929075
CAS:1217338-97-0
Purity:99.94% Package:1removed

BMS-929075 manufacturers

  • BMS-929075
  • BMS-929075 pictures
  • $190.00 / 1mg
  • 2026-04-13
  • CAS:1217338-97-0
  • Min. Order:
  • Purity: 99.94%
  • Supply Ability: 10g
  • BMS-929075
  • BMS-929075 pictures
  • $6.05 / 1ASSAYS
  • 2024-10-22
  • CAS:1217338-97-0
  • Min. Order: 200g
  • Purity: 95.0%-99.0%
  • Supply Ability: 100kg
BMS-929075 Basic information
Product Name:BMS-929075
Synonyms:BMS-929075;3-Benzofurancarboxamide, 4-fluoro-2-(4-fluorophenyl)-N-methyl-5-[2-methyl-5-[[[1-(2-pyrimidinyl)cyclopropyl]amino]carbonyl]phenyl]-;4-Fluoro-2-(4-fluorophenyl)-n-methyl-5-(2-methyl-5-((1-(pyrimidin-2-yl)cyclopropyl)carbamoyl)phenyl)benzofuran-3-carboxamide;BMS-929075, 10 mM in DMSO
CAS:1217338-97-0
MF:C31H24F2N4O3
MW:538.54
EINECS:
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Mol File:1217338-97-0.mol
BMS-929075 Structure
BMS-929075 Chemical Properties
Boiling point 725.5±60.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka12.76±0.20(Predicted)
Safety Information
MSDS Information
BMS-929075 Usage And Synthesis
UsesBMS-929075 is a potent and orally active HCV NS5B replicase palm site allosteric inhibitor. BMS-929075 shows high oral bioavailability. BMS-929075 shows cytotoxicity[1].
in vivo

BMS-929075 (compound 37) (2 mg/kg for i.v.; 6 mg/kg for p.o.) shows good pharmacokinetic parameters with oral bioavailability of 48% in rats[1].
Pharmacokinetic Parameters of BMS-929075 in Male Sprague-Dawley rats[1].

IVPO
speciesCl (mL/min/kg)IV t1/2(hr)Vss(L/kg)Cmax(μM)Tmax(hr)AUC (μM h)C6 liver (μM)C24 liver (μM)C24 liver/plasma (μM)F% (mL/min/kg)
rat1.74.70.77.5454.515.11.121.648
Rats, 2 mg/kg i.v.; 6 mg/kg p.o.[1].
References[1] Yeung KS, et al. Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J Med Chem. 2017 May 25;60(10):4369-4385. DOI:10.1021/acs.jmedchem.7b00328
BMS-929075 Preparation Products And Raw materials
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