PF-4363467

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PF-4363467 Suppliers list
Company Name: Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd  
Tel: 15317229551
Email: 15151849396@163.com
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
PF-4363467 Basic information
Product Name:PF-4363467
Synonyms:PF-4363467;PF 04363467;Benzenesulfonamide, N-[4-[(2R)-4-ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)-
CAS:2040055-84-1
MF:C22H30N2O3S
MW:402.55
EINECS:
Product Categories:
Mol File:2040055-84-1.mol
PF-4363467 Structure
PF-4363467 Chemical Properties
Boiling point 523.8±60.0 °C(Predicted)
density 1.164±0.06 g/cm3(Predicted)
pka8.79±0.10(Predicted)
Safety Information
MSDS Information
PF-4363467 Usage And Synthesis
UsesPF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R[1].
IC 50D3 Receptor: 3.1 nM (Ki); D2 Receptor: 692 nM (Ki)
References[1] Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177. DOI:10.1021/acschemneuro.6b00297
PF-4363467 Preparation Products And Raw materials
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