Substance P (1-7)(TFA)
| 中文名称 | Substance P (1-7)(TFA) |
|---|---|
| 中文同义词 | 神经肽P物质H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-OH;RF-7 |
| 英文名称 | Substance P (1-7)(TFA) |
| 英文同义词 | Substance P (1-7)(TFA) |
| CAS号 | |
| 分子式 | C??H??F?N??O?? |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | 目录多肽 |
| Mol文件 | Mol File |
| 结构式 |
Substance P (1-7)(TFA) 性质
Substance P(1-7) TFA 是神经肽 P 物质 (SP) 的片段。Substance P(1-7) TFA 可对孤束核产生抑制和缓和作用。
Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P(1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.