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| | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) Basic information |
| Product Name: | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) | | Synonyms: | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT);Leukotriene A4 Hydrolase human;LTA-4 hydrolase;LTA4H;Leukotriene A4 Hydrolase from Human, Recombinant;Human LTA4H Protein, His Tag;Recombinant Human LTA4H Protein, His Tag | | CAS: | 90119-07-6 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) Structure]() |
| | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) Chemical Properties |
| | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) Usage And Synthesis |
| Description | Leukotriene A4 hydrolase (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into LTB4, a potent neutrophil chemoattractant.1 In addition to the hydrolase activity, LTA4H also exhibits anion-dependent aminopeptidase activity.1,2 LTA4H is a potential new drug target for a variety of indications associated with leukocyte infiltration to sites of inflammation. Cayman’s LTA4H (human, recombinant) has been expressed and purified from E. coli. Both the epoxide hydrolase and aminopeptidase activities of the enzyme are functional as assessed by measurement of the separate enzyme activities. The enzyme therefore has application for the screening of inhibitors of LTB4 synthesis.WARNING This product is not for human or veterinary use. |
| | LEUKOTRIENE A4 HYDROLASE (HUMAN RECOMBINANT) Preparation Products And Raw materials |
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