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3'-beta-C-Ethynyladenosine manufacturers
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| | 3'-beta-C-Ethynyladenosine Basic information |
| Product Name: | 3'-beta-C-Ethynyladenosine | | Synonyms: | 3'-?C-Ethynyladenosine;3'-beta-C-Ethynyladenosine;Adenosine, 3'-C-ethynyl-;3’-β-C-Ethynyladenosine;3'-C-Ethynyladenosine;3’-beta-C-Ethynyladenosine;(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3,4-diol | | CAS: | 180300-54-3 | | MF: | C12H13N5O4 | | MW: | 291.26 | | EINECS: | | | Product Categories: | | | Mol File: | 180300-54-3.mol |  |
| | 3'-beta-C-Ethynyladenosine Chemical Properties |
| Boiling point | 654.1±65.0 °C(Predicted) | | density | 1.76±0.1 g/cm3(Predicted) | | pka | 11.30±0.70(Predicted) |
| | 3'-beta-C-Ethynyladenosine Usage And Synthesis |
| Uses | 3’-β-C-Ethynyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. 3’-β-C-Ethynyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020 |
| | 3'-beta-C-Ethynyladenosine Preparation Products And Raw materials |
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