BRD2492 (BRD 2492)

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BRD2492 (BRD 2492) Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD  
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Tel: 15865264761
Email: 486064515@qq.com

BRD2492 (BRD 2492) manufacturers

  • BRD2492
  • BRD2492 pictures
  • $30.00
  • 2026-07-11
  • CAS:1821669-43-5
  • Purity: 99.56%
  • Supply Ability: 10g
BRD2492 (BRD 2492) Basic information
Product Name:BRD2492 (BRD 2492)
Synonyms:BRD2492 (BRD 2492);BRD2492;Benzamide, 4-(acetylamino)-N-[2-amino-5-(4-pyridinyl)phenyl]-;4-Acetamido-N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide
CAS:1821669-43-5
MF:C20H18N4O2
MW:346.38
EINECS:
Product Categories:
Mol File:1821669-43-5.mol
BRD2492 (BRD 2492) Structure
BRD2492 (BRD 2492) Chemical Properties
Boiling point 540.4±50.0 °C(Predicted)
density 1.321±0.06 g/cm3(Predicted)
form Solid
pka12.81±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
BRD2492 (BRD 2492) Usage And Synthesis
DescriptionBRD2492 is a novel potent HDAC1/2 inhibitor.
UsesBRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01μM and 11.13μM for T-47D and MCF-7 cells, respectively[1].
IC 50HDAC1: 13.2 nM (IC50); HDAC2: 77.2 nM (IC50); HDAC3: 8908 nM (IC50); HDAC6: >1000 nM (IC50)
References[1] Linda Schker-Hübner, et al. Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors. ChemMedChem. 2022 May 4;17(9):e202100755. DOI:10.1002/cmdc.202100755
BRD2492 (BRD 2492) Preparation Products And Raw materials
Tag:BRD2492 (BRD 2492)(1821669-43-5) Related Product Information
4-(3-amino-4-(pyridin-4-yl)benzamido)benzoic acid Benzoic acid, 4-[[4-(4-pyridinyl)benzoyl]amino]- N-(3-amino-2-methylphenyl)isonicotinamide N-[4'-(isonicotinoylamino)[1,1'-biphenyl]-4-yl]isonicotinamide N-[2-(isonicotinoylamino)phenyl]isonicotinamide N-methyl-N-phenylpyridine-4-carboxamide