DBCO-PEG4-triethoxysilane

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DBCO-PEG4-triethoxysilane Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:DBCO-PEG4-triethoxysilane
CAS:2353410-02-1
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Alfa Chemistry
Tel: +1-5166625404;
Email: Info@alfa-chemistry.com
Products Intro: Product Name:DBCO-PEG4-triethoxysilane
CAS:2353410-02-1
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:DBCO-PEG4-triethoxysilane
CAS:2353410-02-1
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
Tel: +86-15680926068
Email: 1924344760@confluore.cn
Products Intro: Product Name:DBCO-PEG4-Silane
CAS:2353410-02-1
Purity:>99.00% Package:25mg
Company Name: Aladdin Scientific
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Email: tp@aladdinsci.com
Products Intro: Product Name:DBCO-PEG4-triethoxysilane
CAS:2353410-02-1
Purity:98% Package:$1621.9/50mg;$2551.9/100mg;$5041.9/250mg;Bulk package Remarks:98%

DBCO-PEG4-triethoxysilane manufacturers

  • DBCO-PEG4-Silane
  • DBCO-PEG4-Silane pictures
  • 2025-06-07
  • CAS:2353410-02-1
  • Min. Order: 25mg
  • Purity: >99.00%
  • Supply Ability: 100mg
DBCO-PEG4-triethoxysilane Basic information
Product Name:DBCO-PEG4-triethoxysilane
Synonyms:DBCO-PEG4-triethoxysilane;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(20,20-diethoxy-15-oxo-3,6,9,12,21-pentaoxa-16-aza-20-silatricos-1-yl)-γ-oxo-;DBCO-PEG4-Silane
CAS:2353410-02-1
MF:C39H57N3O10Si
MW:755.98
EINECS:
Product Categories:
Mol File:2353410-02-1.mol
DBCO-PEG4-triethoxysilane Structure
DBCO-PEG4-triethoxysilane Chemical Properties
Boiling point 900.0±65.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
pka15.14±0.46(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
DBCO-PEG4-triethoxysilane Usage And Synthesis
DescriptionDBCO-PEG4-triethoxysilane is a PEG linker containing a triethoxysilane moiety and a DBCO group. Triethoxysilane is commonly used for surface modifications. DBCO group can react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG chain increasse the water solubility of a compound in aqueous media.
UsesDBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-triethoxysilane is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-PEG4-triethoxysilane Preparation Products And Raw materials
Tag:DBCO-PEG4-triethoxysilane(2353410-02-1) Related Product Information
Propanoic acid, 3-[2-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-PEG3-OH 4,7,10,13,16,19,22,25-Octaoxa-28-azadotricosanoic acid, 32-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-29,32-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-C6-acid DBCO-PEG2-amine DBCO-PEG4-maleimide DBCO-PEG3-Mal 4,7,10-Trioxa-13-azaheptadecanoic acid, 17-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-14,17-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-Acid DBCO-PEG1 DBCO-PEG4-biotin DBCO-NHCO-PEG2-Biotin Ambient temperature 1H-Pyrrole-1-propanamide, N-[2-[2-[3-[[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethyl]-2,5-dihydro-2,5-dioxo- DBCO-PEG4-Acid N-(6-aminocaproyl)azadibenzocyclooctyne