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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85563444 18351873721 |
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| Products Intro: |
Product Name:t-Boc-Aminooxy-PEG7-bromide
CAS:2353410-15-6
Purity:95%HPLC Package:50mg;100mg;250mg;1g
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| | t-Boc-Aminooxy-PEG7-bromide Basic information |
| Product Name: | t-Boc-Aminooxy-PEG7-bromide | | Synonyms: | t-Boc-Aminooxy-PEG7-bromide;3,6,9,12,15,18,21,24-Octaoxa-2-azahexacosanoic acid, 26-bromo-, 1,1-dimethylethyl ester;t-Boc-Aminooxy-PEG7-bromid boc | | CAS: | 2353410-15-6 | | MF: | C21H42BrNO10 | | MW: | 548.46 | | EINECS: | | | Product Categories: | | | Mol File: | 2353410-15-6.mol |  |
| | t-Boc-Aminooxy-PEG7-bromide Chemical Properties |
| density | 1.214±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF |
| | t-Boc-Aminooxy-PEG7-bromide Usage And Synthesis |
| Description | t-Boc-Aminooxy-PEG7-bromide is a crosslinking reagent. The hydrophilic PEG7 spacer increases solubility in aqueous media. Bromide (Br) is a very good leaving group for nucleophilic reactions. The t-Boc-Aminooxy can be deprotected under mild acidic conditions. | | Uses | t-Boc-Aminooxy-PEG7-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | t-Boc-Aminooxy-PEG7-bromide Preparation Products And Raw materials |
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