BMS-284640

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Company Name: BOC Sciences  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: Guangzhou Ruidi Biotechnology Co., Ltd.  
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Email: sales@ubiochem.com
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
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BMS-284640 manufacturers

  • BMS-284640
  • BMS-284640 pictures
  • $2500.00
  • 2026-07-15
  • CAS:230640-88-7
  • Purity:
  • Supply Ability: 10g
BMS-284640 Basic information
Product Name:BMS-284640
Synonyms:BMS-284640;CHEMBL51879;UNII-XP87V064PV;XP87V064PV;BMS284640,BMS 284640;Cyclopropanecarboxamide, N-(aminoiminomethyl)-3-(2,3-dihydro-4-benzofuranyl)-2,2-dimethyl-, (1R,3R)-
CAS:230640-88-7
MF:C15H19N3O2
MW:273.33
EINECS:
Product Categories:
Mol File:230640-88-7.mol
BMS-284640 Structure
BMS-284640 Chemical Properties
density 1.40±0.1 g/cm3(Predicted)
pka12.82±0.60(Predicted)
Safety Information
MSDS Information
BMS-284640 Usage And Synthesis
UsesBMS-284640 is a synthetic sodium hydrogen exchange isomer-1 (NHE-1) inhibitor. BMS-284640 has a more than 380-fold higher NHE-1 inhibitory activity (IC50: 9 nM) compared to cariporide (HY-19693) and is more selective for NHE-1 over NHE-2 (IC50: 1.8 μM) and NHE-5 (IC50: 3.36 μM). BMS-284640 and its analogs also exhibit enhanced oral bioavailability and prolonged plasma half-life in rats.[1].
References[1] Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1
BMS-284640 Preparation Products And Raw materials
Tag:BMS-284640(230640-88-7) Related Product Information
BenzaMide, 4-(1-acetyl-4-piperidinyl)-N-(aMinoiMinoMethyl)-3-(trifluoroMethyl)- N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine Eniporide hydrochloride EIPA 2-Oxo-Zoniporide Hydrochloride UTX-143