| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PNU-104489 manufacturers
- U 104489
-
- $3400.00
-
2026-07-27
- CAS:177577-60-5
- Purity:
- Supply Ability: 10g
- U 104489
-
- $3400.00
-
2025-07-17
- CAS:177577-60-5
- Purity:
- Supply Ability: 10g
|
| | PNU-104489 Basic information |
| Product Name: | PNU-104489 | | Synonyms: | PNU-104489;Methanesulfonamide, N-[2-[[4-[[3-[(1,1-dimethylethyl)amino]-2-pyridinyl]ethylamino]-1-piperidinyl]carbonyl]-1H-indol-5-yl]-;U 104489;U104489;U-104489 | | CAS: | 177577-60-5 | | MF: | C26H36N6O3S | | MW: | 512.67 | | EINECS: | | | Product Categories: | | | Mol File: | 177577-60-5.mol |  |
| | PNU-104489 Chemical Properties |
| Boiling point | 734.2±70.0 °C(Predicted) | | density | 1.315±0.06 g/cm3(Predicted) | | pka | 9.04±0.30(Predicted) |
| | PNU-104489 Usage And Synthesis |
| Uses | U-104489 is a HIV-1 inhibitor with the Ki values of 0.13, 0.12 and ＞ 100 μM aganist HIV-1 RT p66/p51 wild type (G190), G190A and G190E, respectively[1]. | | References | [1] Fan N, et al. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry. 1996;35(30):9737-9745. DOI:10.1021/bi9600308 |
| | PNU-104489 Preparation Products And Raw materials |
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